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DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures

G-quadruplex existence was proved in cells by using both antibodies and small molecule fluorescent probes. However, the G-quadruplex probes designed thus far are structure- but not conformation-specific. Recently, a core-extended naphthalene diimide (c(ex)-NDI) was designed and found to provide fluo...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Gaglione, Rosa, Napolitano, Ettore, Arciello, Angela, Pirota, Valentina, Doria, Filippo, Musumeci, Domenica, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508963/
https://www.ncbi.nlm.nih.gov/pubmed/34638964
http://dx.doi.org/10.3390/ijms221910624