Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes

Glioblastoma (GBM) is the most frequent and deadliest primary brain cancer in adults, justifying the search for new treatments. Some members of the iron-based ferrocifen family have demonstrated a high cytotoxic effect on various cancer cell lines via innovative mechanisms of action. Here, we evalua...

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Detalles Bibliográficos
Autores principales: Vessières, Anne, Quissac, Emie, Lemaire, Nolwenn, Alentorn, Agusti, Domeracka, Patrycja, Pigeon, Pascal, Sanson, Marc, Idbaih, Ahmed, Verreault, Maïté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508975/
https://www.ncbi.nlm.nih.gov/pubmed/34638742
http://dx.doi.org/10.3390/ijms221910404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508975/
https://www.ncbi.nlm.nih.gov/pubmed/34638742
http://dx.doi.org/10.3390/ijms221910404

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