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Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds

TMEM175 (transmembrane protein 175) coding sequence variants are associated with increased risk of Parkinson’s disease. TMEM175 is the ubiquitous lysosomal K(+) channel regulated by growth factor receptor signaling and direct interaction with protein kinase B (PKB/Akt). In the present study, we show...

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Detalles Bibliográficos
Autores principales: Pergel, Enikő, Veres, Irén, Csigi, Gergely Imre, Czirják, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508992/
https://www.ncbi.nlm.nih.gov/pubmed/34638858
http://dx.doi.org/10.3390/ijms221910515