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A Method to Monitor the NAD(+) Metabolome—From Mechanistic to Clinical Applications

Nicotinamide adenine dinucleotide (NAD(+)) and its reduced form (NADH) are coenzymes employed in hundreds of metabolic reactions. NAD(+) also serves as a substrate for enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs) and ADP-ribosyl cyclases. Given the pivotal role of NAD(H) in health...

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Detalles Bibliográficos
Autores principales: Giner, Maria Pilar, Christen, Stefan, Bartova, Simona, Makarov, Mikhail V., Migaud, Marie E., Canto, Carles, Moco, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508997/
https://www.ncbi.nlm.nih.gov/pubmed/34638936
http://dx.doi.org/10.3390/ijms221910598