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Peptide Location Fingerprinting Reveals Tissue Region-Specific Differences in Protein Structures in an Ageing Human Organ

In ageing tissues, long-lived extracellular matrix (ECM) proteins are susceptible to the accumulation of structural damage due to diverse mechanisms including glycation, oxidation and protease cleavage. Peptide location fingerprinting (PLF) is a new mass spectrometry (MS) analysis technique capable...

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Detalles Bibliográficos
Autores principales: Eckersley, Alexander, Ozols, Matiss, Chen, Peikai, Tam, Vivian, Hoyland, Judith A., Trafford, Andrew, Chan, Danny, Sherratt, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509034/
https://www.ncbi.nlm.nih.gov/pubmed/34638745
http://dx.doi.org/10.3390/ijms221910408