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Alpha-1 Antitrypsin and Hepatocellular Carcinoma in Liver Cirrhosis: SERPINA1 MZ or MS Genotype Carriage Decreases the Risk

Heterozygotes for Z or S alleles of alpha-1-antrypsin (AAT) have low serum AAT levels. Our aim was to compare the risk of hepatocellular carcinoma (HCC) in patients with liver cirrhosis carrying the SERPINA1 MM, MZ and MS genotypes. The study groups consisted of 1119 patients with liver cirrhosis of...

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Detalles Bibliográficos
Autores principales: Rabekova, Zuzana, Frankova, Sona, Jirsa, Milan, Neroldova, Magdalena, Lunova, Mariia, Fabian, Ondrej, Kveton, Martin, Varys, David, Chmelova, Klara, Adamkova, Vera, Hubacek, Jaroslav A., Spicak, Julius, Merta, Dusan, Sperl, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509047/
https://www.ncbi.nlm.nih.gov/pubmed/34638908
http://dx.doi.org/10.3390/ijms221910560