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Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

The plant extract aristolochic acid (AA), containing aristolochic acids I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN), unique renal diseases associated with upper urothelial cancer. Recently (Chemical Research in Toxicology...

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Detalles Bibliográficos
Autores principales: Bárta, František, Dedíková, Alena, Bebová, Michaela, Dušková, Šárka, Mráz, Jaroslav, Schmeiser, Heinz H., Arlt, Volker M., Hodek, Petr, Stiborová, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509051/
https://www.ncbi.nlm.nih.gov/pubmed/34638820
http://dx.doi.org/10.3390/ijms221910479