Cargando…

Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

The plant extract aristolochic acid (AA), containing aristolochic acids I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN), unique renal diseases associated with upper urothelial cancer. Recently (Chemical Research in Toxicology...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bárta, František, Dedíková, Alena, Bebová, Michaela, Dušková, Šárka, Mráz, Jaroslav, Schmeiser, Heinz H., Arlt, Volker M., Hodek, Petr, Stiborová, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509051/ https://www.ncbi.nlm.nih.gov/pubmed/34638820 http://dx.doi.org/10.3390/ijms221910479

Ejemplares similares

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches
por: Martínek, Václav, et al.
Publicado: (2017)

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
por: Dračínská, Helena, et al.
Publicado: (2016)

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
por: Stiborová, Marie, et al.
Publicado: (2015)

DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer
por: Stiborová, Marie, et al.
Publicado: (2017)

Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
por: Stiborová, Marie, et al.
Publicado: (2014)

Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone
por: Arlt, Volker M., et al.
Publicado: (2016)

Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1
por: Milichovský, Jan, et al.
Publicado: (2016)

Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers
por: Stiborová, Marie, et al.
Publicado: (2008)

The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro
por: Sborchia, Mateja, et al.
Publicado: (2019)

Effects of aristolochic acid I and/or hypokalemia on tubular damage in C57BL/6 rat with aristolochic acid nephropathy
por: Yi, Joo-Hark, et al.
Publicado: (2018)

Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms
por: Han, Jiayin, et al.
Publicado: (2019)

The Impact of p53 on Aristolochic Acid I-Induced Gene Expression In Vivo
por: Sborchia, Mateja, et al.
Publicado: (2019)

Aristolochic acid I exposure decreases oocyte quality
por: Li, Weidong, et al.
Publicado: (2022)

Preparation of Anti-Aristolochic Acid I Monoclonal Antibody and Development of Chemiluminescent Immunoassay and Carbon Dot-Based Fluoroimmunoassay for Sensitive Detection of Aristolochic Acid I
por: Ou, Ai-Fen, et al.
Publicado: (2021)

Adenine versus guanine DNA adducts of aristolochic acids: role of the carcinogen–purine linkage in the differential global genomic repair propensity
por: Kathuria, Preetleen, et al.
Publicado: (2015)

Effect of Butylated Hydroxyanisole on the Level of DNA Adduction by Aristolochic Acid in the Rat Forestomach and Liver
por: Routledge, Michael N., et al.
Publicado: (1990)

Update of aristolochic acid nephropathy in Korea
por: Ban, Tae Hyun, et al.
Publicado: (2018)

Overview of aristolochic acid nephropathy: an update
por: Zhou, Qingqing, et al.
Publicado: (2023)

Role of hepatic cytochrome P450 enzymes in the detoxication of aristolochic acid I; effects on DNA adduct, mutation, and tumor formation
por: Luan, Yang, et al.
Publicado: (2015)

Uptake, Translocation, and Fate of Carcinogenic Aristolochic Acid in Typical Vegetables in Soil−Plant Systems
por: Zhang, Jinghe, et al.
Publicado: (2022)

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells
por: Attaluri, Sivaprasad, et al.
Publicado: (2010)

Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease
por: Honarpisheh, Mohsen, et al.
Publicado: (2018)

An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature
por: Jadot, Inès, et al.
Publicado: (2017)

Aristolochic Acid-Induced Genotoxicity and Toxicogenomic Changes in Rodents
por: Li, Xi-Lin, et al.
Publicado: (2020)

Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice
por: Urate, Shingo, et al.
Publicado: (2021)

Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy
por: Juretzko, Annett, et al.
Publicado: (2022)

Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy
por: Tseng, Chiao-Shih, et al.
Publicado: (2011)

Nephroprotective Role of Resveratrol and Ursolic Acid in Aristolochic Acid Intoxicated Zebrafish
por: Ding, Yu-Ju, et al.
Publicado: (2015)

«Suspects» in Etiology of Endemic Nephropathy: Aristolochic Acid versus Mycotoxins
por: Pepeljnjak, Stjepan, et al.
Publicado: (2010)

Mutation signatures implicate aristolochic acid in bladder cancer development
por: Poon, Song Ling, et al.
Publicado: (2015)

Total Synthesis of the Aristolochic Acids, Their Major Metabolites, and Related Compounds
por: Attaluri, Sivaprasad, et al.
Publicado: (2014)

Mass Spectrometric and Spectrofluorometric Studies of the Interaction of Aristolochic Acids with Proteins
por: Li, Weiwei, et al.
Publicado: (2015)

Aristolochic acid exposure in Romania and implications for renal cell carcinoma
por: Turesky, Robert J, et al.
Publicado: (2016)

Temporal Variation of Aristolochia chilensis Aristolochic Acids during Spring
por: Santander, Rocío, et al.
Publicado: (2015)

Aristolochic Acid and Immunotherapy for Urothelial Carcinoma: Directions for unmet Needs
por: Yang, Huang-Yu, et al.
Publicado: (2019)

Bioactivation mechanisms of N‐hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids
por: Okuno, Yoshiharu, et al.
Publicado: (2019)

Assessment of nephrotoxicity of herbal medicine containing aristolochic acid in mice
por: Quan, Yi, et al.
Publicado: (2020)

Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid
por: Wang, Xixin, et al.
Publicado: (2020)

Aristolochic acids exposure was not the main cause of liver tumorigenesis in adulthood
por: Chen, Shuzhen, et al.
Publicado: (2022)

The Presence of Testis Determines Aristolochic Acid-Induced Nephrotoxicity in Mice
por: Li, Wei-Long, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kvu55k6htl7eng92280be7d92d