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A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of genetic variants associated with critical illness (n=35) or hospitalization (n=4...

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Detalles Bibliográficos
Autores principales: Verma, Anurag, Tsao, Noah, Thomann, Lauren, Ho, Yuk-Lam, Iyengar, Sudha, Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana, Efird, Jimmy T., Huffman, Jennifer, Hung, Adriana, Ivey, Kerry, Levin, Michael, Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander, Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita, Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Maryam, Zhao, Hongyu, Ritchie, Marylyn D, Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P., Tsao, Philip S., Gaziano, J. Michael, O’Donnell, Christopher, Damrauer, Scott, Liao, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509103/
https://www.ncbi.nlm.nih.gov/pubmed/34642702
http://dx.doi.org/10.1101/2021.05.18.21257396