Hepatocyte-Specific Deficiency of BAP31 Amplified Acetaminophen-Induced Hepatotoxicity via Attenuating Nrf2 Signaling Activation in Mice

Liver-specific deficiency of B-cell receptor-associated protein 31 knockout mice (BAP31-LKO) and the littermates were injected with acetaminophen (APAP), markers of liver injury, and the potential molecular mechanisms were determined. In response to APAP overdose, serum aspartate aminotransferase an...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Lv, Xiaotong, Huo, Yan, Hu, Xiaodi, Li, Xiaochen, Sun, Shizhuo, Zhao, Xin, Kong, Xuewei, Xu, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509202/
https://www.ncbi.nlm.nih.gov/pubmed/34639126
http://dx.doi.org/10.3390/ijms221910788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509202/
https://www.ncbi.nlm.nih.gov/pubmed/34639126
http://dx.doi.org/10.3390/ijms221910788

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