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Hepatocyte-Specific Deficiency of BAP31 Amplified Acetaminophen-Induced Hepatotoxicity via Attenuating Nrf2 Signaling Activation in Mice
Liver-specific deficiency of B-cell receptor-associated protein 31 knockout mice (BAP31-LKO) and the littermates were injected with acetaminophen (APAP), markers of liver injury, and the potential molecular mechanisms were determined. In response to APAP overdose, serum aspartate aminotransferase an...
Autores principales: | Zhao, Jie, Lv, Xiaotong, Huo, Yan, Hu, Xiaodi, Li, Xiaochen, Sun, Shizhuo, Zhao, Xin, Kong, Xuewei, Xu, Jialin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509202/ https://www.ncbi.nlm.nih.gov/pubmed/34639126 http://dx.doi.org/10.3390/ijms221910788 |
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