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Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions

The three members (GADD45α, GADD45β, and GADD45γ) of the growth arrest and DNA damage-inducible 45 (GADD45) protein family are involved in a myriad of diversified cellular functions. With the aim of unravelling analogies and differences, we performed comparative biochemical and biophysical analyses...

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Detalles Bibliográficos
Autores principales: Smaldone, Giovanni, Caruso, Daniela, Sandomenico, Annamaria, Iaccarino, Emanuela, Focà, Annalia, Ruggiero, Alessia, Ruvo, Menotti, Vitagliano, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509203/
https://www.ncbi.nlm.nih.gov/pubmed/34639041
http://dx.doi.org/10.3390/ijms221910700