Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes

Insulin stimulates glucose uptake in adipose tissue and skeletal muscle by inducing plasma membrane translocation of the glucose transporter GLUT4. Although the small GTPase Rac1 is a key regulator downstream of phosphoinositide 3-kinase (PI3K) and the protein kinase Akt2 in skeletal muscle, it rema...

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Detalles Bibliográficos
Autores principales: Hasegawa, Kiko, Takenaka, Nobuyuki, Tanida, Kenya, Chan, Man Piu, Sakata, Mizuki, Aiba, Atsu, Satoh, Takaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509237/
https://www.ncbi.nlm.nih.gov/pubmed/34639094
http://dx.doi.org/10.3390/ijms221910753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509237/
https://www.ncbi.nlm.nih.gov/pubmed/34639094
http://dx.doi.org/10.3390/ijms221910753

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