Pachymic Acid Attenuated Doxorubicin-Induced Heart Failure by Suppressing miR-24 and Preserving Cardiac Junctophilin-2 in Rats

Defects in cardiac contractility and heart failure (HF) are common following doxorubicin (DOX) administration. Different miRs play a role in HF, and their targeting was suggested as a promising therapy. We aimed to target miR-24, a suppressor upstream of junctophilin-2 (JP-2), which is required to a...

Descripción completa

Detalles Bibliográficos
Autores principales: Younis, Nahla N., Salama, Alaa, Shaheen, Mohamed A., Eissa, Rana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509247/
https://www.ncbi.nlm.nih.gov/pubmed/34639051
http://dx.doi.org/10.3390/ijms221910710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509247/
https://www.ncbi.nlm.nih.gov/pubmed/34639051
http://dx.doi.org/10.3390/ijms221910710

Ejemplares similares