Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands

Thrombin is the key enzyme of the entire hemostatic process since it is able to exert both procoagulant and anticoagulant functions; therefore, it represents an attractive target for the developments of biomolecules with therapeutic potential. Thrombin can perform its many functional activities beca...

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Detalles Bibliográficos
Autores principales: Troisi, Romualdo, Balasco, Nicole, Autiero, Ida, Vitagliano, Luigi, Sica, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509272/
https://www.ncbi.nlm.nih.gov/pubmed/34639143
http://dx.doi.org/10.3390/ijms221910803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509272/
https://www.ncbi.nlm.nih.gov/pubmed/34639143
http://dx.doi.org/10.3390/ijms221910803

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