Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NF-κB Activation: A Review of the Molecular Mechanisms

Chronic (continuous, non-interrupted) hypoxia and cycling (intermittent, transient) hypoxia are two types of hypoxia occurring in malignant tumors. They are both associated with the activation of hypoxia-inducible factor-1 (HIF-1) and nuclear factor κB (NF-κB), which induce changes in gene expressio...

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Detalles Bibliográficos
Autores principales: Korbecki, Jan, Simińska, Donata, Gąssowska-Dobrowolska, Magdalena, Listos, Joanna, Gutowska, Izabela, Chlubek, Dariusz, Baranowska-Bosiacka, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509318/
https://www.ncbi.nlm.nih.gov/pubmed/34639040
http://dx.doi.org/10.3390/ijms221910701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509318/
https://www.ncbi.nlm.nih.gov/pubmed/34639040
http://dx.doi.org/10.3390/ijms221910701

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