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Melatonin as a Therapeutic Agent for the Inhibition of Hypoxia-Induced Tumor Progression: A Description of Possible Mechanisms Involved

Hypoxia has an important role in tumor progression via the up-regulation of growth factors and cellular adaptation genes. These changes promote cell survival, proliferation, invasion, metastasis, angiogenesis, and energy metabolism in favor of cancer development. Hypoxia also plays a central role in...

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Detalles Bibliográficos
Autores principales: Bastani, Sepideh, Akbarzadeh, Moloud, Rastgar Rezaei, Yeganeh, Farzane, Ali, Nouri, Mohammad, Mollapour Sisakht, Mahsa, Fattahi, Amir, Akbarzadeh, Maryam, Reiter, Russel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509383/
https://www.ncbi.nlm.nih.gov/pubmed/34639215
http://dx.doi.org/10.3390/ijms221910874