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Synthesis of Demissidine Analogues from Tigogenin via Imine Intermediates †
A five-step transformation of a spiroketal side chain of tigogenin into an indolizidine system present in solanidane alkaloids such as demissidine and solanidine was elaborated. The key intermediate in the synthesis was spiroimine 3 readily obtained from tigogenin by its RuO(4) oxidation to 5,6-dihy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509427/ https://www.ncbi.nlm.nih.gov/pubmed/34639219 http://dx.doi.org/10.3390/ijms221910879 |