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Synthesis of Demissidine Analogues from Tigogenin via Imine Intermediates †

A five-step transformation of a spiroketal side chain of tigogenin into an indolizidine system present in solanidane alkaloids such as demissidine and solanidine was elaborated. The key intermediate in the synthesis was spiroimine 3 readily obtained from tigogenin by its RuO(4) oxidation to 5,6-dihy...

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Detalles Bibliográficos
Autores principales:	Wojtkielewicz, Agnieszka, Kiełczewska, Urszula, Baj, Aneta, Morzycki, Jacek W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509427/ https://www.ncbi.nlm.nih.gov/pubmed/34639219 http://dx.doi.org/10.3390/ijms221910879

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