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The Phenoxyalkyltriazine Antagonists for 5-HT(6) Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases

Among the serotonin receptors, one of the most recently discovered 5-HT(6) subtype is an important protein target and its ligands may play a key role in the innovative treatment of cognitive disorders. However, none of its selective ligands have reached the pharmaceutical market yet. Recently, a new...

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Detalles Bibliográficos
Autores principales: Sudoł, Sylwia, Cios, Agnieszka, Jastrzębska-Więsek, Magdalena, Honkisz-Orzechowska, Ewelina, Mordyl, Barbara, Wilczyńska-Zawal, Natalia, Satała, Grzegorz, Kucwaj-Brysz, Katarzyna, Partyka, Anna, Latacz, Gniewomir, Olejarz-Maciej, Agnieszka, Wesołowska, Anna, Handzlik, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509428/
https://www.ncbi.nlm.nih.gov/pubmed/34639113
http://dx.doi.org/10.3390/ijms221910773