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At a Crossroads to Cancer: How p53-Induced Cell Fate Decisions Secure Genome Integrity

P53 is known as the most critical tumor suppressor and is often referred to as the guardian of our genome. More than 40 years after its discovery, we are still struggling to understand all molecular details on how this transcription factor prevents oncogenesis or how to leverage current knowledge ab...

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Detalles Bibliográficos
Autores principales: Rizzotto, Dario, Englmaier, Lukas, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509445/
https://www.ncbi.nlm.nih.gov/pubmed/34639222
http://dx.doi.org/10.3390/ijms221910883