Distinct Effects of Interleukin-1β Inhibition upon Cytokine Profile in Patients with Adult-Onset Still’s Disease and Active Articular Manifestation Responding to Canakinumab

Adult-onset Still’s disease (AOSD) is a systemic auto-inflammatory disease characterized by the presence of immunologically mediated inflammation and deficient resolution of inflammation. Canakinumab is an approved IL-1β inhibitor in the treatment of AOSD with a balanced efficacy and safety profile....

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Detalles Bibliográficos
Autores principales: Ghannam, Khetam, Zernicke, Jan, Kedor, Claudia, Listing, Joachim, Burmester, Gerd-R., Foell, Dirk, Feist, Eugen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509487/
https://www.ncbi.nlm.nih.gov/pubmed/34640417
http://dx.doi.org/10.3390/jcm10194400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509487/
https://www.ncbi.nlm.nih.gov/pubmed/34640417
http://dx.doi.org/10.3390/jcm10194400

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