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Distinct Effects of Interleukin-1β Inhibition upon Cytokine Profile in Patients with Adult-Onset Still’s Disease and Active Articular Manifestation Responding to Canakinumab
Adult-onset Still’s disease (AOSD) is a systemic auto-inflammatory disease characterized by the presence of immunologically mediated inflammation and deficient resolution of inflammation. Canakinumab is an approved IL-1β inhibitor in the treatment of AOSD with a balanced efficacy and safety profile....
Autores principales: | Ghannam, Khetam, Zernicke, Jan, Kedor, Claudia, Listing, Joachim, Burmester, Gerd-R., Foell, Dirk, Feist, Eugen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509487/ https://www.ncbi.nlm.nih.gov/pubmed/34640417 http://dx.doi.org/10.3390/jcm10194400 |
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