7,8-Dihydroxiflavone Protects Adult Rat Axotomized Retinal Ganglion Cells through MAPK/ERK and PI3K/AKT Activation

We analyze the 7,8-dihydroxyflavone (DHF)/TrkB signaling activation of two main intracellular pathways, mitogen-activated protein kinase (MAPK)/ERK and phosphatidylinositol 3 kinase (PI3K)/AKT, in the neuroprotection of axotomized retinal ganglion cells (RGCs). Methods: Adult albino Sprague-Dawley r...

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Detalles Bibliográficos
Autores principales: Galindo-Romero, Caridad, Vidal-Villegas, Beatriz, Asís-Martínez, Javier, Lucas-Ruiz, Fernando, Gallego-Ortega, Alejandro, Vidal-Sanz, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509499/
https://www.ncbi.nlm.nih.gov/pubmed/34639236
http://dx.doi.org/10.3390/ijms221910896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509499/
https://www.ncbi.nlm.nih.gov/pubmed/34639236
http://dx.doi.org/10.3390/ijms221910896

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