ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape †

Leukemias derived from the MLL-AF9 rearrangement rely on dysfunctional transcriptional networks. ZNF521, a transcription co-factor implicated in the control of hematopoiesis, has been proposed to sustain leukemic transformation in collaboration with other oncogenes. Here, we demonstrate that ZNF521...

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Detalles Bibliográficos
Autores principales: Chiarella, Emanuela, Aloisio, Annamaria, Scicchitano, Stefania, Todoerti, Katia, Cosentino, Emanuela G., Lico, Daniela, Neri, Antonino, Amodio, Nicola, Bond, Heather Mandy, Mesuraca, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509509/
https://www.ncbi.nlm.nih.gov/pubmed/34639154
http://dx.doi.org/10.3390/ijms221910814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509509/
https://www.ncbi.nlm.nih.gov/pubmed/34639154
http://dx.doi.org/10.3390/ijms221910814

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