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Complete Purging of Ewing Sarcoma Metastases from Human Ovarian Cortex Tissue Fragments by Inhibiting the mTORC1 Signaling Pathway

Restoration of fertility by autologous transplantation of ovarian cortex tissue in former cancer patients may lead to the reintroduction of malignancy via the graft. Pharmacological ex vivo purging of ovarian cortex fragments prior to autotransplantation may reduce the risk of reseeding the cancer....

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Detalles Bibliográficos
Autores principales: Peek, Ronald, Eijkenboom, Lotte L., Braat, Didi D. M., Beerendonk, Catharina C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509560/
https://www.ncbi.nlm.nih.gov/pubmed/34640378
http://dx.doi.org/10.3390/jcm10194362