Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum–Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects

DNA-dependent DNA and RNA polymerases are important modulators of biological functions such as replication, transcription, recombination, or repair. In this work performed in cell-free media, we studied the ability of selected DNA polymerases to overcome a monofunctional adduct of the cytotoxic/anti...

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Detalles Bibliográficos
Autores principales: Hreusova, Monika, Brabec, Viktor, Novakova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509567/
https://www.ncbi.nlm.nih.gov/pubmed/34639179
http://dx.doi.org/10.3390/ijms221910838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509567/
https://www.ncbi.nlm.nih.gov/pubmed/34639179
http://dx.doi.org/10.3390/ijms221910838

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