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Characterizing Binding Interactions That Are Essential for Selective Transport through the Nuclear Pore Complex

Specific macromolecules are rapidly transported across the nuclear envelope via the nuclear pore complex (NPC). The selective transport process is facilitated when nuclear transport receptors (NTRs) weakly and transiently bind to intrinsically disordered constituents of the NPC, FG Nups. These two t...

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Detalles Bibliográficos
Autores principales: Lennon, Kathleen M., Soheilypour, Mohammad, Peyro, Mohaddeseh, Wakefield, Devin L., Choo, Grace E., Mofrad, Mohammad R. K., Jovanovic-Talisman, Tijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509584/
https://www.ncbi.nlm.nih.gov/pubmed/34639238
http://dx.doi.org/10.3390/ijms221910898