Cargando…

Characterizing Binding Interactions That Are Essential for Selective Transport through the Nuclear Pore Complex

Specific macromolecules are rapidly transported across the nuclear envelope via the nuclear pore complex (NPC). The selective transport process is facilitated when nuclear transport receptors (NTRs) weakly and transiently bind to intrinsically disordered constituents of the NPC, FG Nups. These two t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lennon, Kathleen M., Soheilypour, Mohammad, Peyro, Mohaddeseh, Wakefield, Devin L., Choo, Grace E., Mofrad, Mohammad R. K., Jovanovic-Talisman, Tijana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509584/ https://www.ncbi.nlm.nih.gov/pubmed/34639238 http://dx.doi.org/10.3390/ijms221910898

Ejemplares similares

Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex
por: Peyro, Mohaddeseh, et al.
Publicado: (2015)

Nucleoporins’ exclusive amino acid sequence features regulate their transient interaction with and selectivity of cargo complexes in the nuclear pore
por: Peyro, Mohaddeseh, et al.
Publicado: (2021)

Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex
por: Peyro, M., et al.
Publicado: (2015)

Quality control of mRNAs at the entry of the nuclear pore: Cooperation in a complex molecular system
por: Soheilypour, Mohammad, et al.
Publicado: (2018)

FG nucleoporins feature unique patterns that distinguish them from other IDPs
por: Peyro, Mohaddeseh, et al.
Publicado: (2021)

Regulation of RNA-binding proteins affinity to export receptors enables the nuclear basket proteins to distinguish and retain aberrant mRNAs
por: Soheilypour, M., et al.
Publicado: (2016)

Free energy calculations shed light on the nuclear pore complex’s selective barrier nature
por: Matsuda, Atsushi, et al.
Publicado: (2021)

On the nuclear pore complex and its emerging role in cellular mechanotransduction
por: Matsuda, Atsushi, et al.
Publicado: (2022)

Brownian Dynamics Simulation of Nucleocytoplasmic Transport: A Coarse-Grained Model for the Functional State of the Nuclear Pore Complex
por: Moussavi-Baygi, Ruhollah, et al.
Publicado: (2011)

Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2
por: Tobin, Steven J., et al.
Publicado: (2018)

An agent-based model for mRNA export through the nuclear pore complex
por: Azimi, Mohammad, et al.
Publicado: (2014)

The Interaction of CRM1 and the Nuclear Pore Protein Tpr
por: Zhao, Charles L., et al.
Publicado: (2014)

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores
Publicado: (1987)

Enhancement of Transport Selectivity through Nano-Channels by Non-Specific Competition
por: Zilman, Anton, et al.
Publicado: (2010)

Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane
por: Paparelli, Laura, et al.
Publicado: (2016)

Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands
por: Wakefield, Devin L., et al.
Publicado: (2023)

Single molecule characterization of individual extracellular vesicles from pancreatic cancer
por: Lennon, Kathleen M., et al.
Publicado: (2019)

The Yeast Nuclear Pore Complex and Transport Through It
por: Aitchison, John D., et al.
Publicado: (2012)

Energetics of Transport through the Nuclear Pore Complex
por: Ghavami, Ali, et al.
Publicado: (2016)

Nuclear transport of single molecules: dwell times at the nuclear pore complex
por: Kubitscheck, Ulrich, et al.
Publicado: (2005)

Pore performance: artificial nanoscale constructs that mimic the biomolecular transport of the nuclear pore complex
por: Andersson, John, et al.
Publicado: (2022)

Single Extracellular VEsicle Nanoscopy
por: Saftics, Andras, et al.
Publicado: (2023)

Rapid Brownian Motion Primes Ultrafast Reconstruction of Intrinsically Disordered Phe-Gly Repeats Inside the Nuclear Pore Complex
por: Moussavi-Baygi, R., et al.
Publicado: (2016)

Cone-shaped HIV-1 capsids are transported through intact nuclear pores
por: Zila, Vojtech, et al.
Publicado: (2021)

Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer
por: Jorand, Raphael, et al.
Publicado: (2016)

The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism
por: Rout, Michael P., et al.
Publicado: (2000)

Karyopherins regulate nuclear pore complex barrier and transport function
por: Kapinos, Larisa E., et al.
Publicado: (2017)

Conformation of the nuclear pore in living cells is modulated by transport state
por: Pulupa, Joan, et al.
Publicado: (2020)

A designer FG-Nup that reconstitutes the selective transport barrier of the nuclear pore complex
por: Fragasso, Alessio, et al.
Publicado: (2021)

Thermodynamics of Competitive Molecular Channel Transport: Application to Artificial Nuclear Pores
por: Bauer, Wolfgang R., et al.
Publicado: (2010)

Higher Nucleoporin-Importinβ Affinity at the Nuclear Basket Increases Nucleocytoplasmic Import
por: Azimi, Mohammad, et al.
Publicado: (2013)

Karyopherin binding interactions and nuclear import mechanism of nuclear pore complex protein Tpr
por: Ben-Efraim, Iris, et al.
Publicado: (2009)

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore
por: Ohba, Tomoyuki, et al.
Publicado: (2004)

TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis
por: Kim, Sumin, et al.
Publicado: (2023)

Cardiac troponin T in extracellular vesicles as a novel biomarker in human cardiovascular disease
por: Lennon, Kathleen M., et al.
Publicado: (2022)

Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer
por: Jones, Veronica C., et al.
Publicado: (2020)

Mads at the nuclear pore
por: LeBrasseur, Nicole
Publicado: (2002)

The nuclear pore complex
Publicado: (1993)

OCTAGONAL NUCLEAR PORES
por: Gall, Joseph G.
Publicado: (1967)

The nuclear pore complex
por: Adam, Stephen A
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_dmp1f5igdgjcn9ei1p46spg56l