Lysophosphatidic Acid Mediates Imiquimod-Induced Psoriasis-like Symptoms by Promoting Keratinocyte Proliferation through LPAR1/ROCK2/PI3K/AKT Signaling Pathway

Psoriasis is a chronic inflammatory skin disease. Recently, lysophosphatidic acid (LPA)/LPAR5 signaling has been reported to be involved in both NLRP3 inflammasome activation in macrophages and keratinocyte activation to produce inflammatory cytokines, contributing to psoriasis pathogenesis. However...

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Detalles Bibliográficos
Autores principales: Kim, Donghee, Kim, Hyo-Jin, Baek, Jin-Ok, Roh, Joo-Young, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509620/
https://www.ncbi.nlm.nih.gov/pubmed/34639115
http://dx.doi.org/10.3390/ijms221910777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509620/
https://www.ncbi.nlm.nih.gov/pubmed/34639115
http://dx.doi.org/10.3390/ijms221910777

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