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Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways

p53 is a transcription factor that is activated under DNA damage stress and regulates the expression of proapoptotic genes including the expression of growth arrest genes to subsequently determine the fate of cells. To investigate the functional differences of polymorphic p53 codon 72, we constructe...

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Detalles Bibliográficos
Autores principales: Kim, Bu-Yeo, Lee, Seo-Young, Chung, Sun-Ku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509680/
https://www.ncbi.nlm.nih.gov/pubmed/34639134
http://dx.doi.org/10.3390/ijms221910793