Systemic Administration of Recombinant Irisin Accelerates Fracture Healing in Mice

To date, pharmacological strategies designed to accelerate bone fracture healing are lacking. We subjected 8-week-old C57BL/6 male mice to closed, transverse, mid-diaphyseal tibial fractures and treated them with intraperitoneal injection of a vehicle or r-irisin (100 µg/kg/weekly) immediately follo...

Descripción completa

Detalles Bibliográficos
Autores principales: Colucci, Silvia Concetta, Buccoliero, Cinzia, Sanesi, Lorenzo, Errede, Mariella, Colaianni, Graziana, Annese, Tiziana, Khan, Mohd Parvez, Zerlotin, Roberta, Dicarlo, Manuela, Schipani, Ernestina, Kozloff, Kenneth M., Grano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509717/
https://www.ncbi.nlm.nih.gov/pubmed/34639200
http://dx.doi.org/10.3390/ijms221910863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509717/
https://www.ncbi.nlm.nih.gov/pubmed/34639200
http://dx.doi.org/10.3390/ijms221910863

Ejemplares similares