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Systemic Administration of Recombinant Irisin Accelerates Fracture Healing in Mice
To date, pharmacological strategies designed to accelerate bone fracture healing are lacking. We subjected 8-week-old C57BL/6 male mice to closed, transverse, mid-diaphyseal tibial fractures and treated them with intraperitoneal injection of a vehicle or r-irisin (100 µg/kg/weekly) immediately follo...
Autores principales: | Colucci, Silvia Concetta, Buccoliero, Cinzia, Sanesi, Lorenzo, Errede, Mariella, Colaianni, Graziana, Annese, Tiziana, Khan, Mohd Parvez, Zerlotin, Roberta, Dicarlo, Manuela, Schipani, Ernestina, Kozloff, Kenneth M., Grano, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509717/ https://www.ncbi.nlm.nih.gov/pubmed/34639200 http://dx.doi.org/10.3390/ijms221910863 |
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