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Hyperglycemia Altered DNA Methylation Status and Impaired Pancreatic Differentiation from Embryonic Stem Cells

The prevalence of type 2 diabetes (T2D) is rapidly increasing across the globe. Fetal exposure to maternal diabetes was correlated with higher prevalence of impaired glucose tolerance and T2D later in life. Previous studies showed aberrant DNA methylation patterns in pancreas of T2D patients. Howeve...

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Detalles Bibliográficos
Autores principales: Chen, Andy Chun Hang, Huang, Wen, Fong, Sze Wan, Chan, Chris, Lee, Kai Chuen, Yeung, William Shu Biu, Lee, Yin Lau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509790/
https://www.ncbi.nlm.nih.gov/pubmed/34639069
http://dx.doi.org/10.3390/ijms221910729