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The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands

The long and complex Trypanosoma brucei development in the tsetse fly vector culminates when parasites gain mammalian infectivity in the salivary glands. A key step in this process is the establishment of monoallelic variant surface glycoprotein (VSG) expression and the formation of the VSG coat. Th...

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Detalles Bibliográficos
Autores principales: Hutchinson, Sebastian, Foulon, Sophie, Crouzols, Aline, Menafra, Roberta, Rotureau, Brice, Griffiths, Andrew D., Bastin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509897/
https://www.ncbi.nlm.nih.gov/pubmed/34543350
http://dx.doi.org/10.1371/journal.ppat.1009904