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The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways
The most commonly used antifungal drugs are the azole compounds, which interfere with biosynthesis of the fungal-specific sterol: ergosterol. The pathogenic yeast Candida glabrata commonly acquires resistance to azole drugs like fluconazole via mutations in a gene encoding a transcription factor cal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509923/ https://www.ncbi.nlm.nih.gov/pubmed/34591857 http://dx.doi.org/10.1371/journal.pgen.1009582 |