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The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways

The most commonly used antifungal drugs are the azole compounds, which interfere with biosynthesis of the fungal-specific sterol: ergosterol. The pathogenic yeast Candida glabrata commonly acquires resistance to azole drugs like fluconazole via mutations in a gene encoding a transcription factor cal...

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Detalles Bibliográficos
Autores principales:	Vu, Bao Gia, Stamnes, Mark A., Li, Yu, Rogers, P. David, Moye-Rowley, W. Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509923/ https://www.ncbi.nlm.nih.gov/pubmed/34591857 http://dx.doi.org/10.1371/journal.pgen.1009582

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