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The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection

Short-chain fatty acids (SCFAs), which consist of six or fewer carbons, are fermentation products of the bacterial community that inhabits the intestine. Due to an immunosuppressive effect on intestinal tissue, they have been touted as a therapeutic for inflammatory conditions of the bowel. Here, we...

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Detalles Bibliográficos
Autores principales: Pace, Fernanda, Rudolph, Sara E., Chen, Ying, Bao, Bin, Kaplan, David L., Watnick, Paula I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510176/
https://www.ncbi.nlm.nih.gov/pubmed/34612688
http://dx.doi.org/10.1128/Spectrum.01369-21