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The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection
Short-chain fatty acids (SCFAs), which consist of six or fewer carbons, are fermentation products of the bacterial community that inhabits the intestine. Due to an immunosuppressive effect on intestinal tissue, they have been touted as a therapeutic for inflammatory conditions of the bowel. Here, we...
Autores principales: | Pace, Fernanda, Rudolph, Sara E., Chen, Ying, Bao, Bin, Kaplan, David L., Watnick, Paula I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510176/ https://www.ncbi.nlm.nih.gov/pubmed/34612688 http://dx.doi.org/10.1128/Spectrum.01369-21 |
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