The Synthesis and Evaluation of Aminocoumarin Peptidomimetics as Cytotoxic Agents on Model Bacterial E. coli Strains

This work presents the successful synthesis of a library of novel peptidomimetics via Ugi multicomponent reaction. Most of these peptidomimetics contain differently substituted aminocoumarin; 7-amino-4-methylcoumarin and 7-amino-4-(trifluoromethyl) coumarin. Inspired by the biological properties of...

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Detalles Bibliográficos
Autores principales: Kowalczyk, Paweł, Wilk, Monika, Parul, Parul, Szymczak, Mateusz, Kramkowski, Karol, Raj, Stanisława, Skiba, Grzegorz, Sulejczak, Dorota, Kleczkowska, Patrycja, Ostaszewski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510199/
https://www.ncbi.nlm.nih.gov/pubmed/34640121
http://dx.doi.org/10.3390/ma14195725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510199/
https://www.ncbi.nlm.nih.gov/pubmed/34640121
http://dx.doi.org/10.3390/ma14195725

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