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PABPC4 Broadly Inhibits Coronavirus Replication by Degrading Nucleocapsid Protein through Selective Autophagy

Emerging coronaviruses (CoVs) can cause severe diseases in humans and animals, and, as of yet, none of the currently available broad-spectrum drugs or vaccines can effectively control these diseases. Host antiviral proteins play an important role in inhibiting viral proliferation. One of the isoform...

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Detalles Bibliográficos
Autores principales: Jiao, Yajuan, Kong, Ning, Wang, Hua, Sun, Dage, Dong, Sujie, Chen, Xiaoyong, Zheng, Hao, Tong, Wu, Yu, Hai, Yu, Lingxue, Huang, Yaowei, Wang, Huan, Sui, Baokun, Zhao, Ling, Liao, Ying, Zhang, Wen, Tong, Guangzhi, Shan, Tongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510267/
https://www.ncbi.nlm.nih.gov/pubmed/34612687
http://dx.doi.org/10.1128/Spectrum.00908-21