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Synthesis and Characterisation of Novel Tricyclic and Tetracyclic Furoindoles: Biological Evaluation as SAHA Enhancer against Neuroblastoma and Breast Cancer Cells

The dihydropyranoindole structures were previously identified as promising scaffolds for improving the anti-cancer activity of histone deacetylase inhibitors. This work describes the synthesis of related furoindoles and their ability to synergize with suberoylanilide hydroxamic acid (SAHA) against n...

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Detalles Bibliográficos
Autores principales: Bingul, Murat, Arndt, Greg M., Marshall, Glenn M., Black, David StC., Cheung, Belamy B., Kumar, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510456/
https://www.ncbi.nlm.nih.gov/pubmed/34641289
http://dx.doi.org/10.3390/molecules26195745