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The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G(2) Arrest in Cryptococcus

The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response to the host lung environment that are critical for host adaptation and subsequent disease. We analyzed the in vivo and in vitro cell cycles to identify key aspects of the C. neoformans cell cycle that are importa...

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Detalles Bibliográficos
Autores principales: Altamirano, Sophie, Li, Zhongming, Fu, Man Shun, Ding, Minna, Fulton, Sophie R., Yoder, J. Marina, Tran, Vy, Nielsen, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510536/
https://www.ncbi.nlm.nih.gov/pubmed/34634930
http://dx.doi.org/10.1128/mBio.02509-21