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Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses

Complement-opsonized HIV-1 triggers efficient antiviral type I interferon (IFN) responses in dendritic cells (DCs), which play an important role in protective responses at the earliest stages in retroviral infection. In contrast, HIV-1 suppresses or escapes sensing by STING- and MAVS-associated sens...

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Detalles Bibliográficos
Autores principales: Posch, Wilfried, Bermejo-Jambrina, Marta, Steger, Marion, Witting, Christina, Diem, Gabriel, Hörtnagl, Paul, Hackl, Hubert, Lass-Flörl, Cornelia, Huber, Lukas A., Geijtenbeek, Teunis B. H., Wilflingseder, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510548/
https://www.ncbi.nlm.nih.gov/pubmed/34634939
http://dx.doi.org/10.1128/mBio.02408-21