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Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses
Complement-opsonized HIV-1 triggers efficient antiviral type I interferon (IFN) responses in dendritic cells (DCs), which play an important role in protective responses at the earliest stages in retroviral infection. In contrast, HIV-1 suppresses or escapes sensing by STING- and MAVS-associated sens...
Autores principales: | Posch, Wilfried, Bermejo-Jambrina, Marta, Steger, Marion, Witting, Christina, Diem, Gabriel, Hörtnagl, Paul, Hackl, Hubert, Lass-Flörl, Cornelia, Huber, Lukas A., Geijtenbeek, Teunis B. H., Wilflingseder, Doris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510548/ https://www.ncbi.nlm.nih.gov/pubmed/34634939 http://dx.doi.org/10.1128/mBio.02408-21 |
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