Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease

A novel class of benzamide-hydroxypyridinone (HPO) derivatives were innovatively designed, synthesised, and biologically evaluated as potential multitargeting candidates for the treatment of Alzheimer's disease (AD) through pharmacophores-merged approaches based on lead compounds 18d, benzyloxy...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaoying, Guo, Jianan, Zhang, Changjun, Gu, Jinping, Zhou, Tao, Bai, Renren, Xie, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510601/
https://www.ncbi.nlm.nih.gov/pubmed/34607518
http://dx.doi.org/10.1080/14756366.2021.1978081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510601/
https://www.ncbi.nlm.nih.gov/pubmed/34607518
http://dx.doi.org/10.1080/14756366.2021.1978081

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