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The contribution of electrostatics to hydrogen exchange in the unfolded protein state

Although electrostatics have long been recognized to play an important role in hydrogen exchange (HX) with solvent, the quantitative assessment of its magnitude in the unfolded state has hitherto been lacking. This limits the utility of HX as a quantitative method to study protein stability, folding...

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Detalles Bibliográficos
Autores principales: Dass, Rupashree, Corlianò, Enrico, Mulder, Frans A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510857/
https://www.ncbi.nlm.nih.gov/pubmed/34370996
http://dx.doi.org/10.1016/j.bpj.2021.08.003