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Novel role of the dietary flavonoid fisetin in suppressing rRNA biogenesis

The nucleolus of a cell is a critical cellular compartment that is responsible for ribosome biogenesis and plays a central role in tumor progression. Fisetin, a nutraceutical, is a naturally occurring flavonol from the flavonoid group of polyphenols that has anti-cancer effects. Fisetin negatively i...

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Detalles Bibliográficos
Autores principales: Kammerud, Sarah C., Metge, Brandon J., Elhamamsy, Amr R., Weeks, Shannon E., Alsheikh, Heba A., Mattheyses, Alexa L., Shevde, Lalita A., Samant, Rajeev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510891/
https://www.ncbi.nlm.nih.gov/pubmed/34267320
http://dx.doi.org/10.1038/s41374-021-00642-1