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Construction of a rAAV-SaCas9 system expressing eGFP and its application to improve muscle mass

An ideal rAAV gene editing system not only effectively edits genes at specific site, but also prevents the spread of the virus from occurring off-target or carcinogenic risks. This is important for gene editing research at specific site in vivo. We report a single rAAV containing SaCas9 and guide RN...

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Detalles Bibliográficos
Autores principales: Weng, Shaoting, Zhao, Yitian, Yu, Changhong, Wang, Xiaofan, Xiao, Xuehan, Han, Liqiang, Zhang, Kunpeng, Wang, Jiang, Yang, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510912/
https://www.ncbi.nlm.nih.gov/pubmed/34590222
http://dx.doi.org/10.1007/s10529-021-03183-1