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Construction of a rAAV-SaCas9 system expressing eGFP and its application to improve muscle mass
An ideal rAAV gene editing system not only effectively edits genes at specific site, but also prevents the spread of the virus from occurring off-target or carcinogenic risks. This is important for gene editing research at specific site in vivo. We report a single rAAV containing SaCas9 and guide RN...
Autores principales: | Weng, Shaoting, Zhao, Yitian, Yu, Changhong, Wang, Xiaofan, Xiao, Xuehan, Han, Liqiang, Zhang, Kunpeng, Wang, Jiang, Yang, Guoyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510912/ https://www.ncbi.nlm.nih.gov/pubmed/34590222 http://dx.doi.org/10.1007/s10529-021-03183-1 |
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